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A semi-automatic computerized method to measure baroreflex-mediated heart rate responses that reduces interobserver variability BJMBR
Soares,P.P.S.; Ushizima,M.R.; Krieger,E.M.; Irigoyen,M.C.C..
Arterial baroreflex sensitivity estimated by pharmacological impulse stimuli depends on intrinsic signal variability and usually a subjective choice of blood pressure (BP) and heart rate (HR) values. We propose a semi-automatic method to estimate cardiovascular reflex sensitivity to bolus infusions of phenylephrine and nitroprusside. Beat-to-beat BP and HR time series for male Wistar rats (N = 13) were obtained from the digitized signal (sample frequency = 2 kHz) and analyzed by the proposed method (PRM) developed in Matlab language. In the PRM, time series were low-pass filtered with zero-phase distortion (3rd order Butterworth used in the forward and reverse direction) and presented graphically, and parameters were selected interactively. Differences...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Baroreflex sensitivity; Heart rate; Blood pressure; Phenylephrine; Nitroprusside.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000600018
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The role of nitric oxide in reproduction BJMBR
McCann,S.M.; Mastronardi,C.; Walczewska,A.; Karanth,S.; Rettori,V.; Yu,W.H..
Nitric oxide (NO) plays a crucial role in reproduction at every level in the organism. In the brain, it activates the release of luteinizing hormone-releasing hormone (LHRH). The axons of the LHRH neurons project to the mating centers in the brain stem and by afferent pathways evoke the lordosis reflex in female rats. In males, there is activation of NOergic terminals that release NO in the corpora cavernosa penis to induce erection by generation of cyclic guanosine monophosphate (cGMP). NO also activates the release of LHRH which reaches the pituitary and activates the release of gonadotropins by activating neural NO synthase (nNOS) in the pituitary gland. In the gonad, NO plays an important role in inducing ovulation and in causing luteolysis, whereas in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: NO and synthase; NG-monomethyl-L-arginine; Nitroprusside; NOergic neurons; FSH; LH; LHRH; FSHRF.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001100007
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